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What is “The Entourage Effect”?

Hello, and welcome to Plantz educational shorts. Today, I will address a critical concept underpinning the modern pharmacology of cannabis-based therapeutics: the entourage effect.  This term, first articulated by Dr. Raphael Mechoulam and Shimon Ben-Shabat in 1998, describes the synergistic interaction between phytocannabinoids, terpenoids, and flavonoids naturally present in Cannabis sativa L., which modulate the...

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